Value chain CAR-T Cell
Research and Development
In Vitro
Preclinical Development
In Vivo
Manufacturing and Clinical trials
Patient


- Cleaning
- CGMP
- Cross contamination
- Sterility
- Deviations
- Quality control
- Contaminants detection
- Safety for gene-edited cells : translocation
- Safety for gene-edited cells : anti-nuclease response
- Safety for gene-edited cells : cytokine-independent growth








- Lentivirus
- Retrovirus
- Adeno-Associated Virus (AAV)
- Adenovirus (ADV)
- Gene Gun
- Electroporation
- Lipid chemical methods
- Protein chemical methods
- Mixed chemical methods
- Inorganic methods




- Mouse immunisation
- Phae Display
- In Silico
- Hybridome


- Intracellular Domain
- T-cell activation/transduction
- Engineering : Tandem CAR
- Engineering : iCAR
- Engineering : Ab-coupled TCR (ATCR)


- Tumor/Ag heterogeneity
- Tumor associated Antigen
- Miroenvironment
- Delivery/homing
- Combinations


- Bioproduction
- Scale-Up
- Automate manufacturing
- Automated high-throughput microbioreactor system
- Supply chain logistics
- Tracking process
- Monitoring logistics
- Non-GMP pilot batch
- GMP batch




- Autologus
- Allogenic
- Cell Bank
- Tissue acquisition
- Off the shelf
- Apheresis


- iPS reprogrammation
- Differentiated Cell
- Production Cell
- Safety donor-derived therapies


- Gene modifcation
- Directed reprogrammation
- Construct introduction


- Bioreacteur
- Wave
- Cell factory
- Other








Search
Companies
Aenitis Technologies
Equipment supplier
Aenitis develops innovative patented devices for the continuous handling, without contact or pressure, of suspended cells by the use of acoustic radiation forces (called acoustophoresis). Aenitis focuses on the development and sales of medical devices and lab instruments addressing bioproduction preparation issues in cell and gene therapy.
Mitry-Mory
France
Centre MEARY
Manufacturer
Research structure
AP-HP MEARY Center for Cell and Gene Therapy is among the leaders in the manufacturing of ATMPs, offering cutting-edge expertise to clinicians, research teams, as well as industrial partners for the support and execution of their cell, tissue, and gene therapy clinical trials.
PARIS
France
CHU de Rouen
Manufacturer
Research structure
University hospital of Rouen Normandy advanced therapy facility NORMAcell
Rouen
France
CTIBiotech
Service company
Research structure
Company specializing in dermatocosmetics and oncology research, in particular through 3D bioprinting of complex models and in-house testing. Bio-bank accredited to the Ministry of Education and Research, with more than 50,000 samples in stock and a network of 200 partners.
Meyzieu
France
Etablissement Français du Sang
Manufacturer
Service company
Research structure
The EFS is the sole player in transfusion in France. In addition to its activities of collection, preparation, qualification and distribution of Labile Blood Products (PSL), EFS is a major player in cell and tissue therapies and in the design and production of MTI. Its CDMO activity offers clinical batch production capacities on several platforms.
St Denis
France
Harmonic Pharma
Service company
HARMONIC PHARMA is a deeptech providing the pharmaceutical, chemistry, biotechnology, cosmetics and nutraceutical industry with customized services during compound development projects. HARMONIC PHARMA has developped In Silico predictions tools tailored to profile a compound activity and/or toxicity.
Nancy
France
IPRASENSE
Equipment supplier
IPRASENSE provides cell analysers for real-time monitoring of cell cultures. Our SME, based in the Montpellier area, relies on expertise in holographic imaging acquired with CEA Leti since its creation in 2013. Our instruments focus on both the academic research and the pharmaceutical industry from the cell line development stages up to the bioproduction in GMP environment.
Clapiers
France
Keyrus Life Science
Service company
Keyrus Life Science is a unique Connected Clinical Research & Development Organization. We believe that it is only by making sense of data that mankind can solve the major health challenges it faces. Keyrus Life Science helps connect industry expertise, Life Data Sciences and Digital Enablement to fully leverage both Clinical Research ecosystems and Real-World Evidence/RWE in healthcare, thus enhancing the reliability, innovative capacity, agility, and, above all, speed of execution of Clinical Research activities.
Levallois-Perret
France
LinBox
Service company
With more than 40 years of experience in cryopreservation, quality and regulatory affairs, LinBox can propose solutions related to biobanks and tissues and cells grafts’ cryopreservation.
Bailly Romainvilliers
France
Sangamo Therapeutics France
Research structure
Sangamo Therapeutics is committed to translating ground-breaking science into genomic medicines with the potential to transform patients’ lives using gene therapy, ex vivo gene-edited cell therapy, and in vivo genome editing and gene regulation. Sangamo Therapeutics France is the French subsidiary of Sangamo Therapeutics. Its actitivies are focused on ex vivo gene-edited cell therapy for the treatment of inflammatory and autoimmune diseases.
VALBONNE
France
tebu-bio
Manufacturer
Service company
The strength of our distribution activity through the pan-European branches of our group, lies in our longstanding relationships with our suppliers. This allows us to provide first-rate service and to be the reliable source for reagents critical to our customers’ research and product development. In parallel, access to a broad selection of ethical sources, including collections of biological samples and primary cells, enables us to perform in vitro assays for understanding mechanisms of actions (MOA) and demonstrating proofs of concepts (POC) with a short turnaround time.
Le Perray en Yvelines
France
Thermo Fisher Scientific
Manufacturer
Service company
Equipment supplier
Thermo Fisher Scientific is the world leader in serving science, with revenues of more than $24 billion and approximately 70,000 employees globally. Our mission is to enable our customers to make the world healthier, cleaner and safer.
Les Ulis
France